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Research papers on Mindfulness for anxiety

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  1. Meditation Programs for Psychological Stress and Well-being

    Madhav Goyal, Sonal Singh, Erica Sibinga, et al. · 2014 · JAMA Internal Medicine · 2,328 citations

    IMPORTANCE: Many people meditate to reduce psychological stress and stress-related health problems. To counsel people appropriately, clinicians need to know what the evidence says about the health benefits of meditation. OBJECTIVE: To determine the efficacy of meditation programs in improving stress-related outcomes (anxiety, depression, stress/distress, positive mood, mental health-related quality of life, attention, substance use, eating habits, sleep, pain, and weight) in diverse adult clinical populations. EVIDENCE REVIEW: We identified randomized clinical trials with active controls for placebo effects through November 2012 from MEDLINE, PsycINFO, EMBASE, PsycArticles, Scopus, CINAHL, A

  2. Mindfulness Interventions

    J. David Creswell · 2016 · Annual Review of Psychology · 1,672 citations

    Mindfulness interventions aim to foster greater attention to and awareness of present moment experience. There has been a dramatic increase in randomized controlled trials (RCTs) of mindfulness interventions over the past two decades. This article evaluates the growing evidence of mindfulness intervention RCTs by reviewing and discussing (a) the effects of mindfulness interventions on health, cognitive, affective, and interpersonal outcomes; (b) evidence-based applications of mindfulness interventions to new settings and populations (e.g., the workplace, military, schools); (c) psychological and neurobiological mechanisms of mindfulness interventions; (d) mindfulness intervention dosing cons

  3. Mind the Hype: A Critical Evaluation and Prescriptive Agenda for Research on Mindfulness and Meditation

    Nicholas T. Van Dam, Marieke K. van Vugt, David R. Vago, et al. · 2017 · Perspectives on Psychological Science · 1,503 citations

    During the past two decades, mindfulness meditation has gone from being a fringe topic of scientific investigation to being an occasional replacement for psychotherapy, tool of corporate well-being, widely implemented educational practice, and "key to building more resilient soldiers." Yet the mindfulness movement and empirical evidence supporting it have not gone without criticism. Misinformation and poor methodology associated with past studies of mindfulness may lead public consumers to be harmed, misled, and disappointed. Addressing such concerns, the present article discusses the difficulties of defining mindfulness, delineates the proper scope of research into mindfulness practices, an

  4. Attending to the present: mindfulness meditation reveals distinct neural modes of self-reference

    Norman A. S. Farb, Zindel V. Segal, Helen S. Mayberg, et al. · 2007 · Social Cognitive and Affective Neuroscience · 1,306 citations

    It has long been theorised that there are two temporally distinct forms of self-reference: extended self-reference linking experiences across time, and momentary self-reference centred on the present. To characterise these two aspects of awareness, we used functional magnetic resonance imaging (fMRI) to examine monitoring of enduring traits ('narrative' focus, NF) or momentary experience ('experiential' focus, EF) in both novice participants and those having attended an 8 week course in mindfulness meditation, a program that trains individuals to develop focused attention on the present. In novices, EF yielded focal reductions in self-referential cortical midline regions (medial prefrontal c

  5. A Randomized, Wait-List Controlled Clinical Trial: The Effect of a Mindfulness Meditation-Based Stress Reduction Program on Mood and Symptoms of Stress in Cancer Outpatients

    Michael Speca, Linda E. Carlson, Eileen Goodey, et al. · 2000 · Psychosomatic Medicine · 1,091 citations

    OBJECTIVE: The objective of this study was to assess the effects of participation in a mindfulness meditation-based stress reduction program on mood disturbance and symptoms of stress in cancer outpatients. METHODS: A randomized, wait-list controlled design was used. A convenience sample of eligible cancer patients enrolled after giving informed consent and were randomly assigned to either an immediate treatment condition or a wait-list control condition. Patients completed the Profile of Mood States and the Symptoms of Stress Inventory both before and after the intervention. The intervention consisted of a weekly meditation group lasting 1.5 hours for 7 weeks plus home meditation practice.

  6. Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis

    Lara Hilton, Susanne Hempel, Brett Ewing, et al. · 2016 · Annals of Behavioral Medicine · 989 citations

    BACKGROUND: Chronic pain patients increasingly seek treatment through mindfulness meditation. PURPOSE: This study aims to synthesize evidence on efficacy and safety of mindfulness meditation interventions for the treatment of chronic pain in adults. METHOD: We conducted a systematic review on randomized controlled trials (RCTs) with meta-analyses using the Hartung-Knapp-Sidik-Jonkman method for random-effects models. Quality of evidence was assessed using the GRADE approach. Outcomes included pain, depression, quality of life, and analgesic use. RESULTS: Thirty-eight RCTs met inclusion criteria; seven reported on safety. We found low-quality evidence that mindfulness meditation is associated

  7. Randomized Controlled Trial of Mindfulness Meditation for Generalized Anxiety Disorder

    Elizabeth A. Hoge, Éric Bui, Luana Marques, et al. · 2013 · The Journal of Clinical Psychiatry · 511 citations

    Article Abstract Objective: Mindfulness meditation has met increasing interest as a therapeutic strategy for anxiety disorders, but prior studies have been limited by methodological concerns, including a lack of an active comparison group. This is the first randomized, controlled trial comparing the manualized Mindfulness-Based Stress Reduction (MBSR) program with an active control for generalized anxiety disorder (GAD), a disorder characterized by chronic worry and physiologic hyperarousal symptoms. Method: Ninety-three individuals with DSM-IV-diagnosed GAD were randomly assigned to an 8-week group intervention with MBSR or to an attention control, Stress Management Education (SME), between

  8. Mindfulness Meditation and Psychopathology

    Joseph Wielgosz, Simon B. Goldberg, Tammi R. A. Kral, et al. · 2018 · Annual Review of Clinical Psychology · 443 citations

    Mindfulness meditation is increasingly incorporated into mental health interventions, and theoretical concepts associated with it have influenced basic research on psychopathology. Here, we review the current understanding of mindfulness meditation through the lens of clinical neuroscience, outlining the core capacities targeted by mindfulness meditation and mapping them onto cognitive and affective constructs of the Research Domain Criteria matrix proposed by the National Institute of Mental Health. We review efficacious applications of mindfulness meditation to specific domains of psychopathology including depression, anxiety, chronic pain, and substance abuse, as well as emerging efforts

  9. The Effect of Mindfulness Meditation Training on Biological Acute Stress Responses in Generalized Anxiety Disorder

    Elizabeth A. Hoge, E. Bui, Sophie A. Palitz, et al. · 2017 · Psychiatry research · 188 citations

    Mindfulness-Based interventions have increased in popularity in psychiatry, but the impact of these treatments on disorder-relevant biomarkers would greatly enhance efficacy and mechanistic evidence. If Generalized Anxiety Disorder (GAD) is successfully treated, relevant biomarkers should change, supporting the impact of treatment and suggesting improved resilience to stress. Seventy adults with GAD were randomized to receive either Mindfulness-Based Stress Reduction (MBSR) or an attention control class; before and after, they underwent the Trier Social Stress Test (TSST). Area-Under-the-Curve (AUC) concentrations were calculated for adrenocorticotropic hormone (ACTH) and pro-inflammatory cy

  10. Evaluation of Cognitive Behavioral Therapy vs Mindfulness Meditation in Brain Changes During Reappraisal and Acceptance Among Patients With Social Anxiety Disorder: A Randomized Clinical Trial.

    P. Goldin, Matthew D Thurston, Santiago Allende, et al. · 2021 · JAMA psychiatry · 49 citations

    Importance Cognitive behavioral group therapy (CBGT) and mindfulness-based stress reduction (MBSR) are thought to help patients with social anxiety disorder (SAD) via distinct emotion-regulation mechanisms. However, no study has compared the effects of CBGT and MBSR on brain and negative emotion indicators of cognitive reappraisal and acceptance in patients with SAD. Objective To investigate the effects of CBGT and MBSR on reappraisal and acceptance in patients with SAD and to test whether treatment-associated brain changes are associated with social anxiety symptoms 1 year posttreatment. Design, Setting, and Participants In this randomized clinical trial, a total of 108 unmedicated adul

  11. Enhanced mindfulness-based stress reduction (MBSR+) in episodic migraine: effects on sleep quality, anxiety, stress, and depression: a secondary analysis of a randomized clinical trial

    S. Burrowes, O. Goloubeva, Kristen Stafford, et al. · 2021 · Pain · 35 citations

    Migraine patients suffer from high morbidity related to the repeated headache attacks characteristic of the disorder, poor sleep and a high prevalence of co-morbid psychosocial disorders. Current pharmacological therapies do not address these aspects of migraine, but non-pharmacological treatments such as Mindfulness Based Stress Reduction (MBSR) have been shown to improve both pain and psychological well-being. In this secondary analysis, we examined the change over time in sleep quality and psychosocial outcomes from the MRI Outcomes for Mindfulness Meditation Clinical Trial and assessed how these mediated treatment response (50% reduction in headache frequency post-intervention). We also

  12. Effects of Mindfulness-Based Stress Reduction on Blood Pressure, Mental Health, and Quality of Life in Hypertensive Adult Women: A Randomized Clinical Trial Study

    A. Babak, N. Motamedi, S. Mousavi, et al. · 2022 · The Journal of Tehran University Heart Center · 33 citations

    Background: Hypertension is one of the most important causes of cardiovascular diseases. Patients with hypertension have a lower quality of life. We aimed to evaluate the effects of mindfulness meditation on blood pressure, mental health, and quality of life in patients with hypertension. Methods: This randomized clinical trial was performed in 2019 in Isfahan. Eighty adult women with Stage I or II hypertension were included and assigned randomly to 2 groups: 12 weeks of mindfulness-based stress reduction (MBSR) and routine care. At baseline and 1 week after the end of the intervention, blood pressure, stress, depression, anxiety, and quality of life of the studied participants were measured

  13. Aerobic exercise, mindfulness meditation, and stress-reduction in high-stress, college-based young adults: A pilot study

    G. Zieff, Lee Stoner, B. Frank, et al. · 2022 · Journal of American College Health · 16 citations

    Abstract This pilot study assessed the feasibility and combined effect of aerobic exercise (AE) and mindfulness meditation (MM), compared with MM alone and a control (CON) condition, on stress, anxiety, and depression in high-stress college-based young adults. Thirty-two participants (84.4% F, 20.5 ± 2.7 years, 23.9 ± 5.0 kg/m2) were randomized to a four-week, AE + MM (n = 16), MM (n = 10), or control intervention (n = 6). ANOVA revealed non-significant, but noteworthy group x time interactions (perceived stress: p = 0.09; anxiety/depression: p = 0.07). Both AE + MM and MM seem to be feasible strategies to reduce levels of stress, anxiety and depression in college-based young adults.

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